MLB · 1 month ago

MLB Best Bets Today: Tuesday’s Top 2 Betting Picks (July 22)

Gabriel Santiago

Host · Writer

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There is no stopping us now. The MLB season and summer are fully underway, meaning there are betting opportunities every day between now and October. We’ve got you covered for Tuesday’s baseball slate!

Where to Watch St. Louis Cardinals vs. Colorado Rockies

Ballpark: Coors Field
Location: Denver, CO
Where to Watch: FDSNMW, COLR
Time: 8:40 p.m. ET
Spread: STL -1.5 (-102) | Total: 12
Moneyline: STL -156 | COL +132

Note: All odds are subject to change after article publication. Get the most up-to-date odds here.

Tuesday has me feeling bold, and with that, I am ready to challenge a total at Coors Field.

The Colorado Rockies are set to host the St. Louis Cardinals for the second of three games (STL won 6-2 on Monday). On the mound, we’ll see dueling right-handed hurlers Erick Fedde and Bradley Blalock.

As always, the opportunity for scoring is prevalent at Denver’s lofty elevation. However, considering both lineups on hand, support for “under 12 runs" here could pay dividends.

Blalock has been blitzed in four starts this season, posting a 1.80 WHIP. Still, St. Louis’ offense is not the most imposing. The Cardinals show a .715 team OPS in 2025 but the bats have regressed as of late. Over the past seven outings, the Red Birds have scored just 4.14 runs per game.

Fedde has done well this year to reduce the long ball by allowing 1.09 homers per nine innings (according to FanGraphs), which could prove vital at Coors Field. He’ll face a Colorado lineup that shows a .676 OPS, which is the second-worst offensive clip in the National League.

Scoring a dozen runs in a single contest is no easy task—I think the Cards and Rox fall short of that total on Tuesday.

Best Bet: Under 12 runs

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Where to Watch Milwaukee Brewers vs. Seattle Mariners

Ballpark: T-Mobile Field
Location: Seattle, WA
Where to Watch: FDSNWI, RSNW
Time: 9:40 p.m. ET
Spread: SEA -1.5 (+168) | Total: 6.5 (-124/+102)
Moneyline: MIL +108 | SEA -126

The Seattle Mariners and Milwaukee Brewers are scheduled for Game 2 from T-Mobile Field. For the viewing pleasure of all baseball fans, this bid will feature righties Logan Gilbert and Jacob Misiorowski as projected starters.

Undoubtedly, the Brewers are one of the most exciting squads that MLB has to offer right now. Milwaukee has won 11 consecutive contests and counting. Additionally, Misiorowski — boasting a 3.14 xFIP after five starts — is viewed as the Senior Circuit’s next dominant ace. He’ll face the M’s tonight in a venue that favors pitchers perhaps more than any other; T-Mobile shows a 91 Park Factor score.

Gilbert has also performed well in 2025 but now takes on the daunting task of cooling down the Brewers’ scorching lineup. Milwaukee showcases a slash line of .299/.348/.424 over the past week. From there, the Brew Crew is operating with a .711 OPS against RHP this year.

Seattle is a solid bunch that may find their way to the postseason, but going against a red-hot team from Milwaukee, I am riding with the Crew until proven otherwise. FanDuel Sportsbook still has the Brewers with an underdog listing (+108 odds) for Tuesday, and that’s where my action is.